Chrysin a promising anticancer agent: recent perspectives

Honey, propolis, and passionflower contain a flavone known as chrysin. Researchers are studying chrysin to prove its potential stop cancer cells growth. Chrysin therapeutic is of great interest numerous studies have been done illustrate this potential. It associated protein pathways effectively suppress tumor growth within the body. shown ability kill breast, prostate, lung, liver, stomach cancerous cells. can block Phosphoinositide 3-kinase/protein kinase B/mammalian target rapamycin (PI3K/AKT/mTOR) Mitogen-activated kinase/extracellular signal-regulated (MAPK/ERK) signaling in different animals against various cancers. has breast laboratory setting by inhibiting their cell division. strongly suppresses Matrix metalloproteinase-9 (MMP-9), Urokinase plasminogen activator (uPA) Vascular endothelial factor (VEGF), i.e. factors that cause cancer. androgen receptor (AR), necessary for prostate development metastasis. starts caspase cascade blocks synthesis lung Unnecessary apoptosis be prevented stopping certain pathways. significantly decreased metastasis animal-modeled studies. induces stops colon G2/M cycle phase. cancer-promoting cyclin B1 cyclin-dependent 2. suppressed CDK2 production order prevents spread blocking blood vessel expansion. Chrysin’s solubility, accessibility bioavailability may limit medical use. targets cancer-related communication present reduce chances onset cancer, it also serve an alternative treatment whole prevent treat cancers, but more clinical trials research needed fully unlock